EQS-News: Eckert & Ziegler: PentixaPharm Receives BfArM-Clearance for its Therapeutic to conduct a Clinical Trial in Lymphoma
EQS-News: Eckert & Ziegler Strahlen- und Medizintechnik AG
/ Key word(s): Miscellaneous
Eckert & Ziegler: PentixaPharm Receives BfArM-Clearance for its Therapeutic to conduct a Clinical Trial in Lymphoma
08.06.2023 / 11:31 CET/CEST
The issuer is solely responsible for the content of this announcement.
Würzburg, Bavaria, 8 June 2023. PentixaPharm GmbH, a developer of innovative radiopharmaceuticals fully owned by Eckert & Ziegler Strahlen- und Medizintechnik AG (ISIN DE0005659700; TecDax) has received the approval from the German Federal Institute for Drugs and Medical Devices (BfArM) to start PTT101, its open-label dose escalation study to evaluate the safety, tolerability, biodistribution and efficacy of PentixaTher. The Yttrium-90 labelled CXCR4-compound PentixaTher will be tested as a radiotherapeutic against recurrent or refractory primary or isolated secondary central nervous system lymphoma.
The phase I/II, dose-finding study will be conducted at the University Hospital in Essen, North Rhine Westphalia, Germany. “After showing up to 90% of CNS lymphoma patients overexpressing the target CXCR4 with the Ga68-labeled tracer PentixaFor in CNS lymphoma patients, we are happy to test now the therapeutic impact when attacking CXCR-4 with [90Y]Y-PentixaTher (yttrium (90Y) anditixafortide). The study will start after getting final endorsement from the German Radiation Safety Department (BfS),“ commented Dr. Hakim Bouterfa, Chief Medical Officer at Eckert & Ziegler.
In addition, radiolabelled PentixaTher has shown outstanding results under named-patient programs in patients with T-cell lymphoma as conducted at the University Hospital Würzburg (DOI: 10.2967/jnumed.122.264207) (1).
1) Buck AK, Grigoleit GU, Kraus S, Schirbel A, Heinsch M, Dreher N, Higuchi T, Lapa C, Hänscheid H, Samnick S, Einsele H, Serfling SE, Werner RA. C-X-C Motif Chemokine Receptor 4-Targeted Radioligand Therapy in Patients with Advanced T-Cell Lymphoma. J Nucl Med. 2023 Jan;64(1):34-39. doi: 10.2967/jnumed.122.264207. Epub 2022 Jun 23. PMID: 35738903; PMCID: PMC9841250.
About Eckert & Ziegler.
Eckert & Ziegler Strahlen- und Medizintechnik AG with more than 1.000 employees is a leading specialist for isotope-related components in nuclear medicine and radiation therapy. The company offers a broad range of services and products for the radiopharmaceutical industry, from early development work to contract manufacturing and distribution. Eckert & Ziegler shares (ISIN DE0005659700) are listed in the TecDAX index of Deutsche Börse. Contributing to saving lives.
For enquiries please contact:
Eckert & Ziegler AG, Karolin Riehle, Investor Relations
Robert-Rössle-Str. 10, 13125 Berlin, Germany
Tel.: +49 (0) 30 / 94 10 84-138, [email protected], www.ezag.com
08.06.2023 CET/CEST Dissemination of a Corporate News, transmitted by EQS News - a service of EQS Group AG. The issuer is solely responsible for the content of this announcement.
The EQS Distribution Services include Regulatory Announcements, Financial/Corporate News and Press Releases. Archive at www.eqs-news.com
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Language: |
English |
Company: |
Eckert & Ziegler Strahlen- und Medizintechnik AG |
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Robert-Rössle-Str.10 |
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13125 Berlin |
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Germany |
Phone: |
+49 30 941084-138 |
Fax: |
+49 30 941084-112 |
E-mail: |
[email protected] |
Internet: |
www.ezag.de |
ISIN: |
DE0005659700 |
WKN: |
565970 |
Indices: |
SDAX, TecDAX |
Listed: |
Regulated Market in Frankfurt (Prime Standard); Regulated Unofficial Market in Berlin, Dusseldorf, Hamburg, Munich, Stuttgart, Tradegate Exchange |
EQS News ID: |
1652711 |
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End of News |
EQS News Service |
1652711 08.06.2023 CET/CEST
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2017 |
2018 |
2019 |
2020 |
2021 |
2022 |
2023 |
Umsatzerlöse1 |
138,63 |
168,71 |
178,49 |
176,14 |
180,44 |
222,26 |
246,09 |
EBITDA1,2 |
26,62 |
32,14 |
43,13 |
44,64 |
57,04 |
55,52 |
58,83 |
EBITDA-Marge3 |
19,20 |
19,05 |
24,16 |
25,34 |
31,61 |
24,98 |
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EBIT1,4 |
17,97 |
23,39 |
32,06 |
33,69 |
47,45 |
44,54 |
45,45 |
EBIT-Marge5 |
12,96 |
13,86 |
17,96 |
19,13 |
26,30 |
20,04 |
18,47 |
Jahresüberschuss1 |
15,12 |
16,89 |
22,48 |
23,11 |
34,66 |
29,75 |
26,77 |
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10,91 |
10,01 |
12,59 |
13,12 |
19,21 |
13,39 |
10,88 |
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26,83 |
21,21 |
40,43 |
36,79 |
33,86 |
34,30 |
47,40 |
Ergebnis je Aktie8 |
0,70 |
0,78 |
1,07 |
1,11 |
1,66 |
1,41 |
1,26 |
Dividende8 |
0,20 |
0,30 |
0,42 |
0,45 |
0,50 |
0,50 |
0,17 |
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Wirtschaftsprüfer: Forvis Mazars
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INVESTOR-INFORMATIONEN |
©boersengefluester.de |
Eckert & Ziegler |
WKN |
Kurs in € |
Einschätzung |
Börsenwert in Mio. € |
565970 |
41,840 |
Halten |
885,83 |
KGV 2025e |
KGV 10Y-Ø |
BGFL-Ratio |
Shiller-KGV |
26,15 |
26,39 |
0,99 |
46,03 |
KBV |
KCV |
KUV |
EV/EBITDA |
4,01 |
18,69 |
3,60 |
14,54 |
Dividende '22 in € |
Dividende '23 in € |
Div.-Rendite '23 in % |
Hauptversammlung |
0,50 |
0,05 |
0,12 |
18.06.2025 |
Q1-Zahlen |
Q2-Zahlen |
Q3-Zahlen |
Bilanz-PK |
13.05.2025 |
09.08.2024 |
14.11.2024 |
27.03.2025 |
Abstand 60Tage-Linie |
Abstand 200Tage-Linie |
Performance YtD |
Performance 52 Wochen |
-2,88% |
-1,10% |
1,31% |
28,74% |
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